The PUM1 Antibody (Y83) from MyBioSource.com is a Rabbit Polyclonal antibody to PUM1, and Pumilio. This antibody recognizes Human, and Mouse antigen. The PUM1 Antibody (Y83) has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
PUM1 is a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. This protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of this protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation